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Learning to breathe under the guidance of Mike White has
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Number of Alveoli in the Human Lung
Ochs M, Nyengaard JR, Jung A, Knudsen L, Voigt M, Wahlers T, Richter J,
Gundersen HJ.
Anatomy, Division of Electron Microscopy, University of Gottingen, Gottingen,
Germany.
The number of alveoli is a key structural determinant of lung architecture.
A design-based stereological approach was used for the direct and unbiased
estimation of alveolar number in the human lung. The principle is based on
two-dimensional topology in three-dimensional space and is free of
assumptions on the shape, size or spatial orientation of alveoli. Alveolar
number is estimated by counting their openings at the level of the free
septal edges, where they form a two-dimensional network. Mathematically, the
Euler number of this network is estimated using physical dissectors at a
light microscopic level. In six adult human lungs, the mean alveolar
number was 480 million (range: 274 to 790 million; CV: 37%). Alveolar number
was closely related to total lung volume with larger lungs having
considerably more alveoli. The mean size of a single alveolus was rather
constant with 4.2x10(6) micro m(3) (range: 3.3 to 4.8x10(6) micro m(3); CV:
10%), irrespective of the lung size. One mm(3) lung parenchyma would then
contain around 170 alveoli. The method proved to be very efficient and easy
to apply in practice. Future applications will show this approach to be an
important addition to design-based stereological methods for the
quantitative analysis of lung structure.
PMID: 14512270 [PubMed - as supplied by publisher]
When you enlarge the lungs you increase the number of
alveoli. This increases the oxygen transfer capability as well as blood
oxygen.
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Coming to The Optimal Breathing School has
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...I felt taller, my posture improved, I could
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